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Discover how Semaphore helped Helix scale operations, automate workflows, and ensure compliance for one of the largest exome sequencing labs in the world.
Contact usHelix is a leading personal genomics company, leveraging DNA to empower individuals to improve their lives. As one of the world’s largest exome sequencing labs, Helix processes and securely stores massive volumes of customer DNA data for research, clinical, and nonclinical applications.
Helix faced the challenge of scaling its operations to handle exponential growth in daily sample throughput while maintaining CLIA and CAP compliance, reducing human error, and ensuring seamless system integration across its lab processes.
Semaphore worked with Helix to design custom LIMS workflows that automated critical lab processes, integrating seamlessly with Helix's instrumentation. This foundational step ensured every stage of the wet lab workflow, from extraction to sequencing, operated efficiently and aligned with Helix's growth objectives.
To minimize manual intervention, Semaphore developed a messaging system between BaseSpace Clarity LIMS and internal tools. This system enabled lab technicians to manage samples with minimal effort, such as requeuing or canceling processes, ensuring smooth operations without disrupting throughput.
Semaphore implemented the extended Clarity LIMS with a strict validation process to ensure it met CLIA and CAP accreditation standards. This included testing and staging processes that allowed continuous lab operations and positioned Helix for scalable growth without compromising high throughput.
Recognizing Helix's dynamic nature, Semaphore provided extensive training to Helix's internal software team, enabling them to maintain and update the solution. This ensured Helix retained full control of its system while Semaphore remained available for future collaboration as needed.
Semaphore’s custom workflows and automation solutions enabled Helix to scale operations seamlessly, managing exponential increases in daily sample throughput while reducing manual intervention and associated errors.
The extended Clarity LIMS ensured CLIA and CAP compliance, while seamless integration across lab processes allowed Helix’s lab to support diverse applications and research partnerships effectively.
Semaphore’s custom workflows and automation solutions enabled Helix to scale operations seamlessly, managing exponential increases in daily sample throughput while reducing manual intervention and associated errors.
The extended Clarity LIMS ensured CLIA and CAP compliance, while seamless integration across lab processes allowed Helix’s lab to support diverse applications and research partnerships effectively.
Semaphore’s partnership with Helix exemplifies how a tailored, client-centered approach to lab informatics can drive growth and operational success. The collaboration began with a thorough assessment of Helix’s needs, leading to the development of automated workflows that optimized lab processes and integrated seamlessly with instrumentation. By addressing critical challenges, such as reducing human error and maintaining compliance, Semaphore provided Helix with a robust solution capable of handling rapid growth.
Through automation and a messaging system that minimized manual intervention, Helix’s lab achieved unprecedented efficiency and reliability. Semaphore’s implementation process was meticulously planned, ensuring no disruption to Helix’s high-throughput operations. Training the internal software team empowered Helix to maintain its solution independently, reinforcing the lab’s ability to adapt and innovate. This combination of technical rigor and collaboration positioned Helix for long-term success.
The case study highlights Semaphore’s ability to implement scalable solutions that maintain lab compliance and quality control. This is a critical achievement for labs facing rapid growth and increasing operational demands in high-stakes environments.
Semaphore’s commitment to client empowerment ensures labs like Helix are equipped for future challenges. By fostering collaboration and providing training, Semaphore delivers solutions that adapt to evolving needs while maintaining compliance and efficiency.
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