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What Do We Normally Do in a LIMS Implementation Project?

If your lab is considering investing in a laboratory information management system (LIMS), you might be wondering what exactly the process looks like.

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A Consultant’s Perspective of a Clinical Lab’s Software Stack

Next-generation sequencing (NGS) clinical laboratories rely on different types of software to meet their business and laboratory needs. Leading laboratories often work with experienced software consultants to make sure that each piece of software is verified and validated, and set up using the best software engineering practices, integrations, and automations.

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Moving Beyond the Happy Path: 5 Key Considerations for a Successful LIMS Implementation

Labs that are implementing a laboratory information management system (LIMS) generally start with “happy path” use cases. These ideal or expected workflows represent the most efficient, smoothest route to complete a task.

view blog

Want to Safeguard Your Lab Data? Five Questions to Ask Your IT Team or LIMS Vendor

Busy labs collect an incredible amount of data every day. From patient and sample data and test results to information about equipment, reagents, and personnel, data is the foundation of the lab business.

view blog

Deconstructing Laboratory Informatics: 6 Disciplines Combine to Enhance Lab Performance

Laboratory informatics is a specialized field that combines multiple disciplines to optimize operations for labs facing increasing competition and a changing technology landscape.

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Mapping Lab Systems the Right Way: Workflow vs. State Diagrams

Workflow and state diagrams play a crucial role in documenting and visualizing laboratory systems. Both are invaluable for labs implementing a laboratory information management system (LIMS) or adding automations to streamline laboratory operations, reduce errors and redundancies, and ensure regulatory compliance. However, each type of diagram serves a distinct purpose.

7
min read
Business Analysis
Lab Software
LIMS Implementation

Where Do Spreadsheets Fit in a Modern Lab’s Informatics Strategy?

Spreadsheets are not always the best tool for every use case in today’s labs. When do they work, and when do they not work?

6
min read
Lab Software
Lab Scaling
Business Analysis
Data Management
Error Reduction

How Simulation Can Improve Efficiency and Drive Innovation in Your Production Lab

Many production labs still rely on spreadsheets for planning, but simulation technologies offer a far more powerful way to optimize workflows, predict outcomes, and drive efficiency. By leveraging process models, 3D simulations, and digital twins, labs can improve scheduling, budgeting, resource allocation, and overall performance without disrupting live operations.

7
min read
Simulation
Business Analysis

How Digital Twins Can Help Labs Improve Performance

Digital twins provide laboratories with a powerful way to simulate process changes, predict outcomes, and optimize performance using real-time data. By leveraging digital twin technology, labs can reduce downtime, improve resource allocation, enhance quality control, and make data-driven decisions, ultimately driving efficiency and ROI without disrupting operations.

7
min read
Simulation

How to Make a LIMS Support Your Lab’s Unique Workflows

If your lab solely relies on default LIMS workflows, you’re missing out on efficiencies that could give your business a competitive advantage.

9
min read
Business Analysis
Error Reduction
Integrations
Lab Automations
LIMS Implementation

How Can You Ensure Entities and Workflows Are Properly Managed Within a LIMS?

To get the best return on investment for a LIMS Implementation, you need to ensure that it’s set up to manage your lab’s entities and workflows properly.

9
min read
LIMS Implementation
Data Management
Business Analysis
Lab Software
LIMS Selection

Why Should Clinical Diagnostics Labs Care About Ontology?

No conversation about data is complete without also considering the ontology used.

9
min read
Technical Concepts
Data Management
Lab Software

Which Type of Integration is the Right One: Direct or Indirect?

The differences between direct and indirect system integrations.

15
min read
Integrations
Lab Automations
Error Reduction
Liquid Handlers

What You Need to Know about Lab Software to Scale Your Throughput Quickly

For labs wanting to scale quickly and efficiently, we’ve identified five key factors related to lab software, particularly laboratory information management systems (LIMS), that can help you minimize the challenges and ensure a smoother ramp-up of throughput.

20
min read
Lab Automations
Error Reduction
Lab Scaling
Integrations

What Labs Need to Know About Software Testing

It’s easier and significantly more cost-effective to build in testing from the beginning of a software project rather than after the fact.

20
min read
Validation
Quality
Error Reduction
Lab Software
Technical Concepts

What Do We Normally Do in a LIMS Implementation Project?

If your lab is considering investing in a laboratory information management system (LIMS), you might be wondering what exactly the process looks like.

12
min read
Business Analysis
Consultancy
LIMS Implementation
Project Management

What Do We Mean By Software Development Best Practices at Semaphore?

Semaphore has developed our own software development best practices to ensure the implementation meets all the requirements. We’ve found this to be a magic mix — user and regulatory requirements built within sustainable business practices.

7
min read
Technical Concepts
Quality
Lab Software

Software Quality: What Role Does Testing Play?

Investing in automated testing during the initial software build pays significant dividends over time, in terms of efficiency and efficacy, as assays evolve.

9
min read
Quality
Lab Software
Validation

Software Architecture: What Makes it Good or Not?

Clinical diagnostic laboratories must have high-quality software in order to run reliably and efficiently. But quality is about more than just the software code. Quality must also be the foundation of the software architecture.

7
min read
Lab Software
Quality

Selecting a LIMS? Why Services Are Just as Important as the Product

When selecting a LIMS, it’s equally important to consider the services available for the product through the vendor and/or third parties.

8
min read
Consultancy
LIMS Selection
LIMS Implementation

Managing a LIMS Implementation in a Dynamic, Regulated Environment

Once you’ve selected your laboratory information management system (LIMS), it’s time to implement it within your lab’s software environment. A critical part of this process for regulated labs is validating the LIMS and ensuring requirements traceability.

18
min read
Validation
Regulatory Programs
Quality
Lab Software

Liquid Handler Robots: Key Integration Factors to Consider

Integrating a liquid handling robot (LHR) with a laboratory information management system (LIMS) takes a collaborative effort between the lab, the LHR management software vendor, and the integration consultant.

5
min read
Integrations
Lab Automations
Error Reduction
LIMS Implementation

Legacy Software Imposes Significant Challenges on NGS Clinical Diagnostic Labs & Evolving LIMS

Labs that rely on legacy systems may not be aware of the usability limitations of their existing systems. But for users, older software can mean performing tasks less effectively, efficiently, and safely, so that they’re not making the best use of their valuable time.

9
min read
Lab Software
Lab Scaling
LIMS Management

Laboratory Accreditation: What’s Software Got To Do With It?

Certification, accreditation, and federal approvals are a vital part of the business of running a clinical diagnostic lab. Your software plays a big part.

6
min read
Validation
Quality
Lab Software
Regulatory Programs

Lab Software Quality: What is Validation & Why is it Important?

Software quality is a broad topic and often not well understood by clinical diagnostic laboratories, which is why we thought it might be helpful to offer a quick primer.

8
min read
Quality
Validation

How Your SOPs and Lab Software Can Help You Reduce Errors

Let’s take a closer look at how software that closely matches your SOPs can help your lab reduce errors, enhance morale, and improve patient safety.

12
min read
Error Reduction
Quality
Regulatory Programs
Lab Software

How to Overcome the Technical Challenges of Lab Integrations

Some of the key technical challenges labs face with each type of instrument integration and how the right integrator can help you address them.

10
min read
Integrations
Lab Automations

How to Build Excellent Custom Software for Clinical Genomics Labs

Building custom software in the clinical genomics laboratory space is a complex and challenging proposition. However, most times, it’s the only viable option for labs seeking an efficient end-to-end process.

15
min read
Lab Software
Quality
Project Management
Regulatory Programs
Business Analysis

How to Accelerate Your Laboratory Accreditation

It takes effort to gain certification, accreditation, and/or approvals. Working with the right partner to strengthen your software infrastructure and build in automation can help you address regulatory program requirements with minimal overhead.

4
min read
Quality
Lab Software

How Integrations Can Improve Your Lab’s Performance

To keep their highly skilled employees engaged and reduce human error, NGS labs need to minimize both unnecessary duplicated effort and simple repetitive tasks.

5
min read
Lab Automations
Integrations

How Agile and Scrum Can Help You Build Better Clinical Lab Software

The Agile methodology is one of the most common project management methods for software development, and for good reason. Its iterative nature lends itself to an ideal build process.

10
min read
Lab Software
Project Management

Have You Ever Considered Your Lab as a Logistics Supply Chain?

A LIMS with built-in ERP functions could help you manage all the logistics of your lab, from optimizing every aspect of your workflows to delivering results to your customers, all while ensuring regulatory compliance.

8
min read
Lab Scaling
Lab Software
LIMS Implementation

Future-Proofing Your NGS Clinical Diagnostic Lab & LIMS

For laboratory and technical leads who want to future-proof their business with a solution that is more agile, scalable, and usable, I propose considering the following actions.

6
min read
Lab Scaling
Lab Software
LIMS Management

Four Ways to Ensure Your Cloud-based LIMS Keeps Patient Data Safe

Cloud-based laboratory information management systems (LIMS) are highly scalable and conveniently accessible. They handle automatic updates and patches so that the software is always current. Plus, they provide state-of-the-art security to ensure sensitive patient data doesn’t fall into the wrong hands. However, because labs operate in a sector where patient privacy is paramount, many hesitate to transition to the cloud.

10
min read
LIMS Selection
LIMS Implementation

File- or API-based Integrations: Which is Best for Liquid Handlers?

When you’re automating your clinical lab, one of the first things you should look for is an opportunity to integrate instruments with your laboratory information management system (LIMS). This is a great way to reduce manual processing and boost the lab’s speed, efficiency, and accuracy.

7
min read
Integrations
Lab Automations

Complex Lab Software: How to Best Manage it With Version Control

Whether you build or buy your LIMS, code version control is key part of managing any complex software system.

8
min read
LIMS Management
Data Management
Quality
Lab Software
Technical Concepts

Build vs. Buy: Which is the Right Informatics Strategy for Your Lab?

Are you trying to decide if your lab should build its own custom software, buy off-the-shelf software (knowing you’ll inevitably have to customize it), or just keep stumbling along with Excel and paper-based tracking? The answer to this question will ultimately depend on your short- and long-term information system (informatics) strategy.

15
min read
LIMS Selection
LIMS Implementation
Project Management

Barcodes in the Lab: How to Maximize Efficiency and Reduce Errors

Barcoding is extremely useful in a lab environment. It lets you quickly and automatically identify and track items like samples, plates, and reagents. But implementing a lab barcode system is not as simple as charging up a scanner and getting to work.

10
min read
Barcodes

6 Powerful Ways to Automate Your Next-Generation Sequencing Lab

For low-throughput labs, manual processing might be the simplest and best way to operate. But for high-throughput labs, automation is the key tool needed to boost speed and efficiency.

6
min read
Lab Automations
Lab Scaling

When to Call in the Software Experts, and How to Get the Best Results

The success of any clinical diagnostic laboratory software project depends on multiple factors—including how much preparation the lab has done before calling in a consultant, whether they have a thorough understanding of their requirements, and if they have identified specific areas where they need help.

5
min read
Consultancy
LIMS Implementation

What Should You Realistically Expect to Pay for a LIMS? Consider These Important Factors

When we talk to labs about choosing a laboratory information management system (LIMS), a common question we’re asked is: What will a system cost?

3
min read
LIMS Implementation

How to Know It’s Time to Replace Your Lab Information Management Software

“Do we need a new laboratory information management system (LIMS) or can we make do with our current system?” This is a question we often hear from labs struggling to make their existing software do what they need.

5
min read
LIMS Implementation
LIMS Selection
LIMS Management

What Do Standard Operating Procedures Have To Do With Your Lab Software?

It might come as a surprise to some laboratory managers, but a lab’s standard operating procedures (SOPs) offer software consultants key insights into the workings of your lab. They also describe how your lab software should behave—assuming they are up to date.

2
min read
Error Reduction
Quality
Regulatory Programs

How Your Lab Can Represent Workflows Effectively

Day-to-day lab operations rely on workflows to manage people, tasks, and systems so that work follows a consistent process every time. Defined workflows help ensure that all the steps are done in the correct order, are free from errors, and meet regulatory requirements.

6
min read
Business Analysis

The Right Consultant Can Help You Improve Profitability and Growth

Optimizing an NGS Clinical Diagnostic laboratory for growth is no small task. Laboratory and technical leads, and other stakeholders, understand full well the complexity of the business and recognize the risk in hiring the wrong consultants to help them modernize their software and update their technology.

3
min read
Consultancy

Strategies for Managing Your Lab Software Stack

NGS clinical diagnostic labs face growing complexity in their software solutions as they attempt to adapt to a market with evolving requirements and stakeholder expectations. It’s not that they want to add to their systems in a piecemeal fashion—it’s quite the opposite. Most lab managers would prefer to buy a single complete solution that meets all of their current and future needs.

3
min read
Lab Software

A Consultant’s Perspective of a Clinical Lab’s Software Stack

Next-generation sequencing (NGS) clinical laboratories rely on different types of software to meet their business and laboratory needs. Leading laboratories often work with experienced software consultants to make sure that each piece of software is verified and validated, and set up using the best software engineering practices, integrations, and automations.

10
min read
Integrations
Lab Software

Choosing the Best LIMS for Your Molecular Diagnostics Lab

When molecular diagnostic labs select a laboratory information management system (LIMS), they typically consider the documented list of features and benefits, as they should. Each LIMS has its strengths and weaknesses, so it’s important to consider these when assessing which system best meets the lab’s unique requirements. However, we’ve seen labs regretfully overlook a number of other factors that can have lasting consequences on their efficiency and profitability.

5
min read
Business Analysis
LIMS Selection

Should You Integrate LIMS Data with a Data Warehouse or Use Data Federation?

Every lab manager knows that good data is essential for advancing science — whether it’s to track trends, confirm or disprove hypotheses, or compare results across experiments. But what’s the best way to ensure decisions are based on good data in your lab environment?

10
min read
Data Management
Integrations

How to Set Up Your Software Environment for Maximum Productivity in the Lab

A standardized testing process lets you implement new changes to your informatics systems the same way every time, which enables a more reliable and repeatable flow.

15
min read
Lab Automations
Lab Scaling
Lab Software
LIMS Implementation
Quality

What is Data Provenance & Why is it Important in the Clinical Diagnostics Space?

In clinical diagnostics labs, there’s a pressing need for data provenance—tracing the origin and changes over time of critical data such as electronic health records, analytical results, and workflow records.

6
min read
Technical Concepts

How to Mitigate Three Common Liquid Handler Robot Problems

Liquid handling robots (LHRs) are commonly used by labs working at scale. Because they reduce the need for manual processing, they can be hugely beneficial or even essential for labs with high throughput.

10
min read
Barcodes
Liquid Handlers

Unlocking Growth: 7 Essential Factors for Scaling Your NGS Lab Successfully

Successfully scaling a next-generation sequencing (NGS) lab takes careful preparation. Myriad complexities are involved, any of which could cause delays and extra expense.

6
min read
Lab Scaling

Applying FAIR Principles to Lab Data: Six Challenges You Might Face

Clinical diagnostic laboratories can gain a significant advantage by ensuring their data conforms to FAIR principles — that is, data is easily findable, accessible, interoperable, and reusable. But many labs don’t recognize the importance of FAIR data or they find that implementing these principles is challenging.

8
min read
Data Management
Lab Software

How to Visualize and Implement a Continuous Improvement Pipeline in a Clinical Laboratory Context

Clinical diagnostic laboratories may have business goals that include increasing profits, reducing costs, or accelerating innovation. Continuous improvement is an organized approach to identifying opportunities to achieve these types of goals.

7
min read
Consultancy
Quality

Software Quality and Lab Quality: What’s the Difference?

In clinical laboratories, quality is a foundational principle. It ensures reliable, accurate, and precise test results. Fortunately, a number of standards can guide you, and common steps can help ensure your software is high quality.

6
min read
Lab Software
Quality
Top Posts

Iterating a Validated Assay? You Need Effective Change Management

Change management can help labs both manage changes and prepare people for change. However, the quality of your change management processes can have a big impact on your success.

5
min read
LIMS Management
Top Posts

Innovation and Growth Drive the NGS Clinical Diagnostic Industry

Next-generation sequencing (NGS) clinical diagnostic labs are playing a key role in efforts to assess the spread of the COVID-19 virus and to develop a vaccine and therapeutics. At the same time, they continue to collaborate and innovate, develop breakthroughs, and advance patient outcomes. In this post, we look at a few standout examples.

4
min read
Industry Updates
Lab Scaling

A Free Open-Source Library for BaseSpace Clarity LIMS

The Semaphore Clarity Library makes complex sample management easier, letting you easily codify your lab process. BaseSpace Clarity LIMS enables thorough customization to your laboratory environment through the use of the Rapid Scripting Application Programming Interface (API).

10
min read
LIMS Implementation
Lab Software

Choosing a Lab Informatics Strategy: What’s Best for Your Startup?

We commonly see labs go through three distinct stages as their business matures. At each stage, we recommend choosing a system that provides just the capabilities truly necessary. But we also recommend labs be prepared to make adjustments as their needs change.

12
min read
Lab Software

From Paper to Digital: How One Molecular Pathology Lab Upgraded its Informatics

A lab’s informatics system is critical for its effective operation. As we discussed in a previous post, in the early stages of a lab’s business development, a complex system might not be necessary—the lab could simply use word processing or spreadsheet software. But as labs develop new tests and ramp up throughput, a robust informatics system becomes increasingly necessary. In a highly regulated environment where reproducibility and accuracy are of utmost importance, paper isn’t a good option for tracking sensitive data.

4
min read
Case Studies
EMR/EHR
Lab Software
Project Management

Why and How You Should Automate Workflow Tests for Clarity LIMS

In clinical diagnostic laboratories, end-to-end testing of complex LIMS workflows is a critical part of the laboratory validation process. Performing these tests manually takes a Herculean effort. They’re hugely time-consuming and prone to error.

5
min read
Lab Automations
LIMS Management

Moving Beyond the Happy Path: 5 Key Considerations for a Successful LIMS Implementation

Labs that are implementing a laboratory information management system (LIMS) generally start with “happy path” use cases. These ideal or expected workflows represent the most efficient, smoothest route to complete a task.

5
min read
Error Reduction
Lab Automations
LIMS Implementation
LIMS Selection

Want to Safeguard Your Lab Data? Five Questions to Ask Your IT Team or LIMS Vendor

Busy labs collect an incredible amount of data every day. From patient and sample data and test results to information about equipment, reagents, and personnel, data is the foundation of the lab business.

10
min read
Data Management

Deconstructing Laboratory Informatics: 6 Disciplines Combine to Enhance Lab Performance

Laboratory informatics is a specialized field that combines multiple disciplines to optimize operations for labs facing increasing competition and a changing technology landscape.

20
min read
Consultancy
Lab Software
Top Posts
LIMS Management

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